Spider-Man and Venom: Maximum Carnage is a side-scrolling beat ’em up game for the Super Nintendo Entertainment System and Mega Drive/Genesis, developed by Software Creations and published by Acclaim Entertainment and its subsidiary LJN in 1994. The game, based on the comic book story arc of the same name, features numerous heroes, including Spider-Man, Venom, and their allies from the Marvel Comics fictional universe like Captain America, Black Cat, Iron Fist, Cloak and Dagger, Deathlok, Morbius and Firestar, all teaming up to battle an onslaught of villains led by Carnage, including Shriek, Doppelganger, Demogoblin and Carrion.

The first prints of the game for the Super NES and Genesis were sold in red-colored cartridges. Later prints came in standard-colored cartridges. It was followed up by a sequel titled Venom/Spider-Man: Separation Anxiety.