Wetrix is a 3D puzzle game, created by Zed Two (now Zee-3 Digital Publishing) and sold to Ocean Software in 1997 for publication on Nintendo 64 in 1998. The game was subsequently ported to personal computers running Microsoft Windows 95/98; to the Sega Dreamcast, as the enhanced remake Wetrix+; and to the Nintendo Game Boy Color, as either simply Wetrix or Wetrix GB.

In 2000, Wetrix received a sequel on the PlayStation 2, entitled Aqua Aqua or on Japanese editions Aquaqua.