BreakThru! (ブレイクスルー) is a tile-matching puzzle video game released for the Windows and MS-DOS in 1994. It was created by the Japanese company Zoo Corporation and published by Spectrum HoloByte, exclusively for the North American market.

The game would later be re-released on a number of different platforms. In the same year the game was ported for the Super NES and the original Game Boy. These two versions were developed by different companies and published by Spectrum HoloByte in North America. A year later, Shoeisha ported/published the game in Japan for the Sega Saturn and PlayStation.